Fallout 76 is an “entirely online” game, Bethesda dev chief Todd Howard confirmed during the company’s E3 media briefing.
But, you can play the game solo.
Vault 76, which is set in West Virginia, includes a story and levelling up, Howard said, but it’s easier to get on playing with other people. There’s also a survival element, although Howard called this “softcore survival”, as opposed to “hardcore survival”.
Source: Eurogamer Fallout 76 is entirely online, but you can play solo