Bus Simulator 18 is the (likely much better) sequel to Bus Simulator 16 that we have a review for here. This game has much better graphics, as it uses Unreal Engine 4, and it does look and sound great. It has full wheel support, though sadly the game is mostly unplayable without a keyboard and mouse available. The main reason is that the menus are clearly meant with mouse support in mind, and occasionally you have to get out of your seat, which requires WASD and mouse controls.
Source: N4G PC Bus Simulator 18 review – ChristCenteredGamer