From GameWatcher: “The Resident Evil 2 Remake is out right now, and it’s one of the best games of the year already. One problem you’ll always come across though is have too many items and too little inventory space. However, with our Resident Evil 2 Remake Discard Items guide we should be able to help.
You’ll always be fighting against the limited inventory space, but you may have missed when it’s fine to discard an item. You have the option at all times, but when can you safely discard items? You definitely won’t need them again… right? We’ve got the answers.”
Source: N4G PC Resident Evil 2 Remake Discard Items – When Can You Safely Discard Items?