Assassin’s Creed Odyssey The Fate of Atlantis Episode 3 has you facing a lot of Isus but one of the final boss fights is a literal superweapon. Crafted by Juno and her husband from the bodies of humans, which is how they made the other beasts Alexios’ has killed, but also the most powerful enemy in their laboratory. Called Hekatonchires, this monster just wants to kill and yearns for death.
Source: N4G PC Assassin's Creed Odyssey The Fate of Atlantis Episode 3 Hekatonchires Boss Fight Guide