During the latest Capcom TV episode, as summarized by ResetERA forums member Dusk Golem, Producer Masachika Kawata confirmed that Resident Evil 3 Remake will be different from the original, with some story events possibly being dramatically changed. The main goal with Resident Evil 2 Remake was to be as faithful as possible to the original, but with the remake of the third entry in the series, Capcom wants to make the characters more interesting.
Source: N4G PC Resident Evil 3 Remake Will Feature Big Changes Over The Original