Responding to a query about frame rate problems from IGN, Capcom said in a statement that performance issues on PC may be linked to the heavy amount of CPU demanded from NPCs in the game.

“In Dragon’s Dogma 2, a large amount of CPU usage is allocated to each character and dynamically calculates the impact of their physical presence in various environments. In certain situations where numerous characters appear simultaneously, the CPU usage can be very high and may affect the frame rate,” a Capcom representative told IGN. “We are aware that in such situations, settings that reduce GPU load may currently have a limited effect; however, we are looking into ways to improve performance in the future.”

Source: N4G PC Capcom Is 'Aware' of Dragon's Dogma 2 Frame Rate Issues on PC